A schematic diagram of the interactions among farm animals, researchers, regulators and the public. Researchers and regulators primarily consider the feasibility of animal genome editing and the food safety of the animal products, respectively. In turn, the public view genome editing and the modified animals based on their sense of ethics. Then, people assess the researchers’ and regulators’ attitudes through their ethical lens. It is important that animal welfare is a priority matter to discuss genome editing in farm animals in society.