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This article in

  1. Vol. 87 No. 4, p. 1218-1246
    unlockOPEN ACCESS
    Received: Aug 22, 2008
    Accepted: Oct 02, 2008
    Published: December 5, 2014

    3 Corresponding author(s):


BOARD-INVITED REVIEW: The biology and regulation of preadipocytes and adipocytes in meat animals12

  1. G. J. Hausman*,
  2. M. V. Dodson†3,
  3. K. Ajuwon,
  4. M. Azain§,
  5. K. M. Barnes#,
  6. L. L. Guan||,
  7. Z. Jiang,
  8. S. P. Poulos,
  9. R. D. Sainz**,
  10. S. Smith††,
  11. M. Spurlock‡‡,
  12. J. Novakofski§§,
  13. M. E. Fernyhough and
  14. W. G. Bergen##
  1. USDA-ARS, Richard B. Russell Agricultural Research Station, Athens, GA 30604;
    Department of Animal Science, Washington State University, Pullman 99164;
    Department of Animal Sciences, Purdue University, West Lafayette, IN 47907;
    Animal and Dairy Science Department, University of Georgia, Athens 30602;
    Division of Animal and Nutritional Sciences, West Virginia University, Morgantown 26506;
    Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Canada T6G 2R3;
    The Coca-Cola Company, Research and Technology, Atlanta, GA 30313;
    Department of Animal Science, University of California, Davis 95616;
    Department of Animal Science, Texas A&M University, College Station 77843;
    Departments of Food Science & Human Nutrition and Animal Sciences, Iowa State University, Ames 50010;
    Department of Animal Sciences, University of Illinois, Urbana 61801; and
    Department of Animal Sciences, Auburn University, Auburn, AL 36849


The quality and value of the carcass in domestic meat animals are reflected in its protein and fat content. Preadipocytes and adipocytes are important in establishing the overall fatness of a carcass, as well as being the main contributors to the marbling component needed for consumer preference of meat products. Although some fat accumulation is essential, any excess fat that is deposited into adipose depots other than the marbling fraction is energetically unfavorable and reduces efficiency of production. Hence, this review is focused on current knowledge about the biology and regulation of the important cells of adipose tissue: preadipocytes and adipocytes.

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