View Full Table | Close Full ViewTable 1.

Blood parameters in steers given a bolus of saline (CON), lipopolysaccharide (LPS-C), or lipopolysaccharide accompanied with a euglycemic clamp (LPS-Eu) during the hypoglycemic phase 180–720 min post-LPS administration

 
Treatment1
P-value
Contrasts
Parameter CON LPS-C LPS-Eu SEM Treatment Time Treatment x Time CON v LPS2 LPS-C v LPS-Eu
Rectal Temperature, °C 38.7a 39.2b 39.2b 0.1 0.02 < 0.01 0.34 0.01 0.95
Metabolites
    NEFA, mEq/L 340a 352a 197b 28 < 0.01 < 0.01 < 0.01 0.08 < 0.01
    BHB,3 mg/dL 4.3a 3.8a 2.7b 0.3 0.01 0.09 0.19 0.02 0.03
    Blood urea N, mg/dL 6.7 10.4 10.1 1.1 0.08 0.01 0.34 0.03 0.84
Haptoglobin, μg/mL 136 170 152 65 0.95 0.19 0.41 0.75 0.87
LBP,4 μg/mL 6.9a 14.0b 12.2b 1.0 < 0.01 < 0.01 < 0.01 < 0.01 0.27
SAA,5 μg/mL 87 117 103 11 0.22 < 0.01 0.32 0.10 0.47
Ionized Calcium, mmol/L 1.40a 1.16b 1.19b 0.02 < 0.01 0.01 0.02 < 0.01 0.38
Complete Blood Count
    Neutrophils, x103/μL 4.4 3.8 1.6 1.1 0.25 0.01 0.08 0.21 0.21
    Lymphocytes, x103/μL 6.0a 2.9b 2.8b 0.6 0.01 < 0.01 0.01 < 0.01 0.89
    Monocytes, x103/μL 0.57a 0.20b 0.18b 0.10 0.03 0.02 0.06 0.01 0.83
    Eosinophils, x103/μL 0.29 0.56 0.46 0.06 0.06 0.05 0.17 0.03 0.27
    Basophils, x103/μL 0.13 0.08 0.07 0.02 0.07 < 0.01 0.04 0.03 0.53
    Red blood cells, x106/μL 9.0 9.4 9.6 0.2 0.26 0.02 0.03 0.11 0.65
    Platelets, x103/μL 553a 274b 256b 31 < 0.01 0.15 0.68 < 0.01 0.71
    NLR6 0.8 1.2 0.6 0.2 0.07 0.12 0.24 0.81 0.03
a,bMeans with different letters differ (P ≤ 0.05).
1CON = saline bolus; LPS-C = LPS bolus; LPS-Eu = LPS bolus and euglycemic clamp.
2LPS-C and LPS-Eu treatments.
3β-hydroxy butyrate.
4Lipopolysaccharide binding protein.
5Serum amyloid A.
6Neutrophil-to-lymphocyte ratio.